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Difference Between Odefsey Vs. Complera

odefsey vs complera

Two major antiviral drugs used in treating HIV are Odefsey and Complera. They contain emtricitabine, rilpivirine, and tenofovir. Gilead Sciences Inc., an American biopharmaceutical company, is the leading manufacturer of both Odefsey and Complera. Learn the Difference Between Odefsey Vs. Complera antiviral drugs, including their uses, dosages, and side effects.

Difference Between Odefsey Vs. Complera

Odefsey and Complera are a complete regimen for HIV therapy. They are combination drugs that work by inhibiting HIV replication. They serve as initial therapy for people who do not have a history of ART. They can also be a replacement if the prescribed drug does not work for HIV treatment.

Dosage

The recommended dosages for Odefsey are as follows:

  • Take one tablet of Odefsey orally once per day. This drug contains 200 mg of emtricitabine, 25 mg of rilpivirine, and 25 mg of tenofovir.
  • For children, the dosage will depend on their weight. However, the usual dosage for this age group is one tablet per day.

The recommended dosages for Complera are as follows:

  • Take one tablet of Complera orally once per day. This drug contains 200 mg of emtricitabine, 25 mg of rilpivirine, and 300 mg of tenofovir.
  • For pediatrics, the dosage will vary depending on their weight. However, the typical dosage for this age group is one tablet per day.

Contraindications and Warnings

Drug interactions can happen if a person takes any of these drugs with other medicines for different treatments. The following medications may contraindicate or interact with Odefsey:

  • Oxcarbazepine
  • Phenobarbital
  • Carbamazepine
  • Rifampin
  • Dexamethasone
  • Rabeprazole

The following list includes the drugs that interact with Complera:

  • Phenytoin
  • Carbamazepine
  • St John’s wort
  • Esomeprazole
  • Rifapentine
  • Dexamethasone

Side Effects

The side effects of Odefsey and Complera are similar. They share exact adverse reactions and precautions. You can expect the following adverse reactions when you are on these medicines:

  • Headache
  • Dizziness
  • Tiredness
  • Depression
  • Skin rashes
  • Nausea
  • Diarrhea
  • Vomiting
  • Insomnia
  • Chest pain
  • Cold sores
  • Difficulty swallowing
  • Fever
  • Weight loss
  • Anxiety
  • Difficulty breathing

Some of these side effects are manageable. If some of these reactions persist and stay for a longer time, consult your doctor immediately. Any sign of hypersensitivity to these medications is dangerous. Tell your doctor at once, and you will receive another HIV treatment prescription.

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