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Category: INSTIs


What are INSTIs?

INSTIs is another antiretroviral medication group design for the treatment of HIV infection. It is an integrase inhibitor use to block the enzyme responsible for the HIV cell replication inside the body. Usually, the health care advisor uses such drugs with the other compositions to treat HIV and avoid complications.

It is not a cure for HIV but the treatment that helps to overcome future complications. Moreover, the use of drugs offers some side effects but they will go away after consistent use or overcome with other medicine usages.

How do INSTIs work?

The person with HIV infection has a poor immune system that reduces the ability to fight against diseases and infections. INSTIs inhibitors effectively stop the replication of the virus inside T-cells and improve the efficiency of the immune system.

As the drug stops enzyme and reduces its efficiency to replicate virus DNA it reduces the amount of HIV inside the body. It increases the resistance and ability to fight back against the infections and have a quality life ahead.

INSTIs drug names

There are multiple drugs available that work as an integrase inhibitor. Some of the names of the drugs are as follows:

  • Bictegravir
  • Dolutegravir
  • Elvitegravir
  • Raltegravir

Side Effects

The use of an integrase inhibitor offers some side effects that vary from person to person. During the treatment, if the side effects are persistent then suggested consulting the health care advisor before stop taking the medicine. Moreover, it is suggested to discuss the allergies with your doctor before start taking the treatment.

Here are some common and other side effects:

  • Mood swings
  • Insomnia
  • Muscles fatigue
  • Headache
  • Dizziness
  • Skin rash or itching
  • Diarrhea or abdominal pain
  • Lightheadedness
  • Kidney problem
  • Liver issues
  • Nausea or vomiting
  • Swelling around face or lips
  • Soreness in throat

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  • What is Isentress (Raltegravir)? Specifically designed to treat people with HIV, Isentress is an HIV drug available by prescription. Isentress is the brand name of Raltegravir. The drug comes in the form of 400mg and 600mg tablets. It is also available under the name Zepdon. How does Isentress work? Isentress is part of a group of medicines called …

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  • What is Tivicay (Dolutegravir)? Controlling HIV has been made easier through the use of ARVs (antiretrovirals), including Tivicay. Also known as Dolutegravir, this medicine is able to provide medical therapy from HIV. It is appropriate for people regardless of age, whether it be children, adolescents, or adults. Tivicay is the brand name Dolutegravir. The drug comes …

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