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Category: NNRTIs


What are NNRTIs (non-nucleoside reverse transcriptase inhibitors)?

The availability of antiretroviral drugs opened great chances for individuals to live a normal, quality life amidst the malicious effects of the human immunodeficiency virus (HIV). These drugs are given depending on the individuals’ health condition and the type of treatment they need. NNRTIs are regarded as non-nucleoside reverse transcriptase inhibitors, which are proven efficient in inhibiting HIV’s replication process and boost the body’s immune system to function better. This group of medicines are also recognized as the primary drugs in providing medical therapy to those who are going through HIV’s malignant effects.

How does NNRTIs function?

Aside from its infectious function, HIV overwhelms the body’s immunity and causes it to fail. This damage alone is enough for the infection to grow and trigger other diseases, which can be hostile and severe. Without the consumption of antiretroviral drugs, it will be very difficult for the treatment to advance.

NNRTIs work by eliminating the viruses’ virulent function towards the body. Commonly, in line with antiretroviral therapy, some of the drugs under NNRTIs need to pair with NRTIs to get effective and better results during the treatment process. However, an individual cannot consume it without the proper dosage provided by the medical specialist.

Available NNRTIs Today

Alongside uncomplicated access to different antiretroviral drugs at the present time, it is easier to take necessary actions in fighting HIV’s virulence.

These medicines are as follows:

  • Nevirapine
  • Efavirenz
  • Rilpivirine
  • Etravirine

Side Effects/Adverse Reactions

Equivalent to other drugs involving treatment for HIV, there are glaring adverse reactions corresponding to the medicines’ strength and performance towards its consumers or recipients. Whether it be mild or severe, it is expected that some of these effects can vanish quickly. However, if the opposite outcome occurs, ensure that you will be administered with immediate medical care.

  • Mild Headache
  • Nausea
  • Fatigue
  • Pain in the muscles
  • Vomiting
  • Dizziness
  • Pain in the abdomen
  • Skin rashes
  • Insomnia and depression

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  • What is Edurant (Rilpivirine)? Acting as an antiretroviral medicine, Edurant assists people who have HIV. Since there is still no cure for the infection, Edurant can be used as therapy. This medication is available for patients 12 years old and above. Its generic name is Rilpivirine. How does Edurant work? As a non-nucleoside reverse transcriptase inhibitor …

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  • What is Intelence (Etravirine)? Also known by its brand label Etravirine, Intelence refers to a form of ART drug (antiretroviral) used to provide relief and medical alleviation for HIV. The medicine is usually utilized with other ART medications, comprising its effectiveness in the field. It applies to individuals who are HIV positive, especially adults and younger children …

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  • What is Sustiva (Efavirenz)? Consumed with other ARTs (antiretroviral drugs) available, Sustiva has become one of the most trusted ART medicines accessible today. It has HIV treatment functions, providing added relief and assistance to thousands of individuals living with this virus.  Sustiva is the brand name of Efavirenz and is also available under the names Efavir and Efcure. How …

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  • What is Nevirapine (Viramune)? Nevirapine refers to a medicinal therapy that has proven great efficiency against HIV. It controls and manages the infection, with its blocking functions to reverse the infectious doings of HIV. The said medicine is administered for adults and even in children aged 15 years up. Nevirapine, the brand name Viramune,  is …

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