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Sovaldi Side Effect. Sofosbuvir (Sovaldi) Uses, Dosage

sovaldi side effect

What is Sofosbuvir (Sovaldi)?

Sofosbuvir is an antiviral drug used for treating the hepatitis C virus (HCV). It is available under the brand name Sovaldi. This prescription medicine is suitable for adults and children at least three years old. Sofosbuvir comes in edible pellet and tablet form.

What is it used for?

Sofosbuvir does not act alone in providing treatment for chronic hepatitis C infection. The prescription will include the combination of another generic drug called Ribavirin. The mixture of these medicines will help reduce the hepatitis C virus in your body. This treatment will prevent the liver from scarring due to liver damage and inflammation.

Sofosbuvir is part of a drug class called miscellaneous antivirals. It is a group of medicine that inhibits the production of viruses that cause infections or diseases. It includes antiviral agents, like Sofosbuvir, that prevent any virus from replicating or multiplying in the body.


Before receiving your prescription with Sofosbuvir, the healthcare professional will check on essential points to ensure your safety and avoid sovaldi side effect. These medical points are the following:

  • Age and weight
  • Medical history
  • Pre-existing medical conditions
  • Other forms of medicines you are currently taking

Once the prescription is ready, it is essential to follow the instructions provided by the healthcare professional. These instructions will help as you start your treatment with Sofosbuvir.

The doses you will see below cater to adults and pediatrics:

Adult dose for hepatitis C infection:

  • Take 400 mg of Sofosbuvir orally per day.
  • Sofosbuvir treatment alongside Ribavirin is weight-based. People who weigh less than 75 kgs will take 1000 mg of Ribavirin. Meanwhile, people who weigh 75 kgs and above will take 1200 mg of Ribavirin.

Pediatric dose for hepatitis C infection:

  • Note that Sofosbuvir is only suitable for children three years and older.
  • Children weighing less than 17 kg – 150 mg of Sofosbuvir once per day is ideal.
  • 17 kg to 35 kg – 200 mg of Sofosbuvir once per day is ideal.
  • 35 kg and above – 400 mg of Sofosbuvir once per day is ideal
  • Children’s dosage with Ribavirin will depend on their weight. Only the healthcare professional will prescribe the right quantity of Sofosbuvir.

How to take it?

Consume Sofosbuvir as directed by the healthcare professional. The prescription label contains instructions on how to take this medicine properly. Ask your healthcare professional for supervision, especially on your first dosage.

Take this medicine with or without food. It is necessary to take it at the same time daily. Most healthcare professionals advise taking Sofosbuvir with food to avoid stomachaches. Do not chew or break the tablet or pellets. You can mix Sofosbuvir with pudding, mashed potato, or chocolate syrup.

Avoid changing your dosage unless your healthcare professional instructs you to. Changing your dosage without consultation can make your treatment with Sofosbuvir less effective. Store Sofosbuvir in an air-tight container at room temperature.

Drug Interactions

Did you ever wonder why your healthcare professional checks on your medical history and other medicines you are taking? It is to ensure your safety with Sofosbuvir and avoid drug interactions.

Drug interactions can be dangerous. Besides making your treatment for hepatitis C less efficient, different health complications can emerge. Some prescription drugs and over-the-counter medicines can interact with Sofosbuvir. It also includes vitamins and herbal products.

Warnings and Precautions

Before using Sofosbuvir, tell your healthcare professional if you have a history of the following conditions and medical activities:

  • Hepatitis B
  • Liver transplant
  • Liver problems
  • Kidney disease
  • Heart disease

If you are pregnant, Sovaldi Side Effect may not be safe for you. This medicine can cause severe congenital disabilities in your unborn baby. Ask your healthcare professional about other antiviral drugs that you can safely use during pregnancy.

Additionally, Sofosbuvir may not be safe if you are hypersensitive to this medicine. Any allergy can be fatal, so avoid using Sofosbuvir if you are allergic to it and its ingredients.

While on your treatment with this medicine, you will need to undergo frequent liver function tests. Since the hepatitis C virus targets the liver, it is essential to know the condition of your liver while taking Sofosbuvir. The tests will also show how your liver reacts to Sofosbuvir treatment.

Sovaldi Side Effects

Like other antiviral medicines, Sofosbuvir also has a set of adverse reactions. We categorized these sovaldi side effect according to their severity. Consider the following:

Mild side effects:

  • Loss of appetite
  • Diarrhea
  • Headache
  • Irritability
  • Weakness
  • Muscle cramps
  • Muscle pain
  • Skin itchiness
  • Nausea
  • Difficulty sleeping

Severe side effects:

  • Fever or chills
  • Lower back pain
  • Ulcers and sores
  • Tiredness
  • Suicidal thoughts
  • Difficulty concentrating
  • Chest pain
  • Lightheartedness
  • Dizziness
  • Shortness of breath
  • Irregular heartbeat

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